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Almost all these reactions are catalyzed by GSTs, and there is a specific one in human cells that can cause the conjugation of GSH to HNE at about 100 times faster rate than the non-enzymatic reaction

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10.1039/c7bm00652g 73 MaX.WenX.YangX.ZhouD.WuQ.FengY.et al (2018)

Comparing the three approaches One reason comparison articles often become misleading is because they assume every treatment is trying to accomplish the same thing