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(Based on [32] ) The mice with HT29 wild type metastatic disease, mostly non angiogenic, did not responded well to treatment with the VEGFA inhibitory antibody B20-4.1.1, however this antibody was effective in significantly reducing the neoplastic bulk in mice injected with ARP2/3 negative HT29 cells

BPC-157 (Body Protection Compound-157) is a 15-amino acid peptide derived from gastric juice proteins, while TB-500 is a synthetic version of Thymosin Beta-4, a naturally occurring 43-amino acid peptide found in high concentrations in blood platelets, wound fluid, and various tissues