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In fact in the face of such blows, Jerne says, 'it was difficult to maintain faith in the selective idea.' He explains 'It seemed unrewarding to present the case to real immunologists, as the instructive theory of antibody formation was firmly entrenched in those daysTo molecular biologists, furthermore, the Natural Selection Theory seemed appalling, because its assumption that protein molecules can be reproduced apparently violated their Central Dogma' (Jerne, 1966)

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Several indirect mechanisms may contribute to feelings of fatigue in patients taking tirzepatide

doi: 10.1080/19768354.2018.1512521 107 MaMZChenGWangPLuWHZhuCFSongMet al