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NFE2L2 serves as the master regulator of antioxidant defense

P184, P197, P1193, P1279 Khramov K

Despite the favorable tolerance observed in humans, proposed side effects have been discussed based on the in vitro effects of BPC-157

Magnetic resonance imaging showed that iron deposition is correlated with cognitive impairment, and this deposition is mainly observed in the hippocampus, cortex, and basal ganglia, where brain cells experience oxidative stress, lipid peroxidation, and increased cystine/Glu transporter expression, iron metabolism, and balance (Ghadery et al., 2015