10.1186/s12964-020-00637-3 54 GurungP.LukensJ
Many mammalian studies have shown that only l-carnitine has beneficial effects ( Reference Liedtke, Nellis and Whitesell 16 Reference Spasov, Iezhitsa and Pisarev 18 ) , while d-carnitine can interfere with the uptake and transport of l-carnitine ( Reference Vernez 13 , Reference Paulson and Shug 19 ) , and therefore inhibit the -oxidation of FA ( Reference Spasov and Iezhitsa 20 , Reference Leichter, Ottem and Hahn 21 ) , which has a hepatotoxic effect ( Reference Arafa 22 )

Disclosures: Jan Clusmann: Nothing to Disclose, Paul-Henry Koop: Nothing to Disclose, David Zhang: Nothing to Disclose, Felix Van Haag: Nothing to Disclose, Omar el Nahhas: Nothing to Disclose, Kai Markus Schneider: Nothing to Disclose, Jakob Nikolas Kather: Nothing to Disclose, Carolin Victoria Schneider: Nothing to Disclose 1934 WILMS TUMOR 1 AND HIF-1 INDUCE HEPATIC STELLATE CELL INVASION THAT DEVELOPS BRIDGING FIBROSIS IN CHRONIC LIVER INJURY Michitaka Matsuda 1 Tatsuya Kanto 1 Ekihiro Seki 2 , 1 National Center for Global Health and Medicine, 2 Cedars-Sinai Medical Center Background: Chronic liver injury induces the production and deposition of extracellular matrix (ECM) and its further remodeling develops Bridging fibrosis (BF)
The mean firing rate (MFR) was calculated as the average of the number of spikes in time per electrode in a well, considering only the active electrodes