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In contrast, static suspension and gel culture failed to reproduce clinical toxicities at similar doses, only showing adverse effects at significantly higher concentrations (~40 M), not aligned with patient-relevant conditions

It can attenuate activity of the NMDA receptor (Majewska et al., 1990), enhance the uptake of glutamate from the synaptic cleft (Lane and Lawen, 2013), and directly inhibit calcium channels, thereby modulating neuronal excitability (Nelson et al., 2007)

Facial paralysis following influenza vaccination: a disproportionality analysis using the vaccine adverse event reporting system database

Ice crystal formation can damage the peptide structure through physical disruption of molecular bonds