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Description

Resident gut microbiota play a dual role in maintaining host homeostasis and immune defense, serving as both essential partners in immune system evolution and potential contributors to AD development through dysbiosis

An indispensable substance for various physiological cellular functions, lactate plays a regulatory role in different aspects of energy metabolism and signal transduction

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Aging is commonly associated with gut dysbiosis, marked by reduced microbial diversity and a decline in beneficial bacterial populations, which has been linked to cognitive decline and increased frailty (Claesson et al., 2012