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Sickle cell disease (SCD) is an abnormality in the hemoglobin molecules causing abnormal red blood cells to shape that are not biconcave discs with a dimple in the center but instead are shaped like a sickle or a crescent moon, resulting in inefficient oxygen transport to the body and rapid red blood cell turnover

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10.1039/d0fo00178c 193 YangY.LiM.WangQ.HuangH.ZhaoY.DuF.et al (2022d)

Adoption Rates: Mounjaro now holds approximately 79% of the dual-agonist market share globally due to its high efficacy-to-safety ratio