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10.1016/j.physbeh.2013.12.003 Physiol

Engineering complex-type N-glycosylation in Pichia pastoris using GlycoSwitch technology

Furthermore, ALS, characterized by progressive motor neuronal loss, currently lacks effective therapies that significantly prolong survival

Combining GPX4 and CDK4/6 inhibition leads to the collapse of the glutathione (GSH)-glutathione peroxidase 4 (GPX4) antioxidant systems that fails to protect against ferroptosis, and it is accompanied by a deep reduction of cell cycle and apoptosis markers 33,47,48