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Set7/9 directly interacts with p65/RelA and modulates NFkB-dependent transcription As an alternative to the H3K4-methylation-dependent mechanism that mediates up-regulation of p65/RelA expression, Li et al

Potential effects include: Increased collagen I and III deposition Improved organization of repair tissue Better tendon and muscle remodeling after injury Support for functional recovery rather than only scar formation These effects are central to why BPC 157 is often positioned as a connective-tissue recovery peptide

Matias I, Diniz LP, Araujo APB, Damico IV, de Moura P, Cabral-Miranda F, Diniz F, Parmeggiani B, de Mello CV, Leite REP, Suemoto CK, Ferreira GC, Kubrusly RCC, Gomes FCA (2023) Age-associated upregulation of glutamate transporters and glutamine synthetase in senescent astrocytes in vitro and in the mouse and human hippocampus