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Figure 3 Similar results were observed in animal experiments using PSO rats, with an increase in Firmicutes and a decrease in Bacteroidota ( Figure 3E )

Intriguingly, the expression of ABC transporters is indeed induced by ROS as a mechanism to counter oxidative stress, and some of these transporters are also implicated in intracellular free heme release and ROS production [32, 33]

Capturing VCP: another molecular piece in the als jigsaw puzzle

Edaravone (EDA), another radical scavenger, has recently shown preclinical potential for treating neurodegenerative diseases including AD through modulation of ferroptosis-related pathways (243, 244)