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72 These astrocytes maintain their interactions with local neurones, synapses, oligodendrocytes and vascular cells but may alter these interactions in accordance with context-specific reactive changes in molecular expression and functions

Additionally, Fer-1, an effective lipid peroxidation inhibitor, can inhibit ferroptosis-related changes in erastin-treated keratinocytes and block inflammation both in vitro and in vivo, reducing cytokine production, and alleviating psoriasiform dermatitis in the imiquimod-induced model [207]

Research further integrates organoid drug screening with multi-omics technologies, systematically analyzing the mechanisms of drug action via transcriptome sequencing and proteomics analysis of drug-treated organoid samples (Toshimitsu et al., 2022

coli strain Rosetta (DE3) (Novagen)