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Laffin says its best to steer clear of this supplement, as there isnt enough conclusive research

In a pentylenetetrazole-induced convulsion model in mice, topiramate pretreatment decreased GSH levels and increased MDA levels, suggesting that TPM negatively regulates oxidative stress (Agarwal et al., 2011)

Chowdhury A, Adak MK, Mukherjee A, Dhak P, Khatun J, Dhak D (2019) A critical review on geochemical and geological aspects of fluoride belts, fluorosis and natural materials and other sources for alternatives to fluoride exposure

(44) The CYP2E1 gene encodes a 56.9 KD enzyme that is capable of metabolizing drugs, hormones and xenobiotic toxins such as ethanol