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doi: 10.18632/oncotarget.13718 56 DharGASahaSMitraPNag ChaudhuriR

They suppress neuronal necroptosis by disrupting the receptor-interacting protein kinase 1 (RIPK1)-RIPK3 interaction and mitigate ferroptosis via the delivery of miR-218a-5p, which triggers a cascade involving B cell-specific Moloney murine leukemia virus integration site 1 (Bmi1)-mediated methyltransferase-like 3 (Mettl 3) degradation, a reduction in ribosomal protein S6 kinase beta-1 (p70S6K) mRNA, and ultimately, decreased lipid peroxidation (77)