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On initial survey, the average GAD-7 score was 5.30 (range 0-15) and average PHQ-9 score 5.75 (range 0-18)

Antiviral therapies, mainly based on the combination of IFN and ribavirin can only assure a long term eradication of the virus in less than half of treated patients

Dysfunctional AT leads to low adiponectin and high leptin levels, causing hepatic insulin resistance and increased lipolysis, further accelarating the development and progression of NAFLD