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J Chromatogr B Analyt Technol Biomed Life Sci 2021;1173:122551

Most therapeutic compounds target a single pathway, but this peptide orchestrates a coordinated biological response through at least six distinct molecular routes

111 Beyond its direct effect on hepatocytes, IL-6 can also indirectly promote liver regeneration by stimulating HSCs to secrete HGF, which mediates mitotic activation and recovery of the residual liver with other extrahepatic factors