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While some newly identified biomarkers are specific to PSC-associated CCA, most serum extracellular vesicle proteins showed strong diagnostic performance in identifying CCA, regardless of disease aetiology, and are thus termed pan-CCA biomarkers

Pregnancy While there are no large, well-controlled studies on the use of sulfamethoxazole and trimethoprim in pregnant women, Brumfitt and Pursell, 11 in a retrospective study, reported the outcome of 186 pregnancies during which the mother received either placebo or sulfamethoxazole and trimethoprim

PMID 15672138

The peroxidation of PL-PUFAs at bis-allylic carbons is catalyzed by ferrous iron and lipoxygenases through Fenton reactions