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A 24-month randomized trial on postmenopausal women found that resveratrol can "reduce chronic pain in age-related osteoarthritis and improve menopause-related quality of life"

The following defensive enzymes found to play a key role in the organism protection against glycoxidation: aldo- and keto-reductases, aldehyde and alcohol dehydrogenases, carbonyl reductases, amadoriases (deglycases), cytochromes P450 family, glutathione reductase, glucose-6-phosphate dehydrogenase, glutathione-S-transferases and glutathione-dependent glyoxalase system (2, 14, 133, 134)