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Eyayu, T., Zeleke, A

doi: 10.1021/acs.jafc.2c01712

This triggers a cascade of effects: accelerated keratinocyte proliferation, increased desquamation (shedding of the outer layer), and stimulation of collagen synthesis in the dermis

For example, gemcitabine thermosensitive hydrogels or microspheres are used for intraperitoneal perfusion to treat peritoneal metastasis, which can form a drug sustained release reservoir in the peritoneal cavity, prolong local exposure time and reduce systemic toxicity (Xu et al., 2016)