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And, it turns out that gut bacteria actually play an essential role in the breakdown of uric acid, too

Cell death of cardiomyocytes and other changes affecting myocardial integrity, such as fibro-fatty replacement, displacement of desmosomal proteins, modulation of the expression of cardiomyocyte ion channel proteins, myocardial fibrosis, were observed (67) and leads to arrhythmic sequelae in acute and post-acute COVID-19 (72)

doi: 10.1016/j.celrep.2018.10.073 195 ChintaKCPaclHTAgarwalASteynAJC

When macrophages are infected, any cellular process can be disrupted and subsequently affect multiple cellular processes