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Description

The objective is to conduct a metabolomic analysis, employing multidimensional and one-dimensional approaches to identify metabolite differences between the two groups and screen potential biomarkers for early LN detection and treatment monitoring

In addition to these conventional sites of mitochondrial ROS generation, it has been recently reported that the branched-chain 2-oxoacid dehydrogenase (BCKDH) complex in mitochondria can produce superoxide and H 2 O 2 at higher rates than complex I from mitochondria (Quinlan et al., 2014)