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(1) This peptide appears to be naturally present in the bloodstream and has been suggested as a potential element in regulating the growth, development, and apoptosis of vascular endothelial cells

IGF-1 possesses both, GH-like actions and insulin-like actions, whose effects in vivo depend on the dosage, length of treatment, and even route of administration [134, 135]

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AOD9604 appears to stimulate proteoglycan and collagen synthesis in chondrocytes through growth factor signaling pathways distinct from its lipolytic mechanism, supporting cartilage matrix repair in joint models