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The term 'nutraceuticals' was first used by de Felice (1989) who, combining the words nutrition and pharmaceuticals, defined them as 'a food (or part of a food) that provides medical or health benefits, including the prevention and treatment of a disease'

The clinical application of ferroptosis as a treatment strategy is nascent, and rigorous clinical trials are needed to establish its efficacy and safety

These data provide strong in vivo evidence that concomitant reduction of cystine uptake, transsulfuration and GPX4 activity can be utilized as a new therapeutic strategy for high-risk, MYCN -amplified neuroblastomas

Vitamin E transfers its hydrogen to superoxide radical of polyunsaturated fatty acids, breaking the radical chain reaction and preventing the peroxidation of polyunsaturated fatty acids in the cellular and subcellular membranes