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Description

Dysfunctional mitochondria generate excessive reactive oxygen species (ROS), perpetuating a vicious cycle that further aggravates neurotoxicity (Yan et al., 2021

NAC at low doses (6001800 mg) has a relatively safe side effect profile

Craig Mello for advice and support with generation of the gst-4 mutant, and Dr

Dludla PV, Mazibuko-Mbeje SE, Nyambuya TM, Mxinwa V, Tiano L, Marcheggiani F, Cirilli I, Louw J, Nkambule BB (2019) The beneficial effects of N-acetyl cysteine (NAC) against obesity associated complications: a systematic review of pre-clinical studies