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The levels of IL6, TNF- and LDH were measured with a microplate reader at 450 nm

Senescent cells are also marked by the senescence-associated secretory phenotype (SASP), which includes pro-inflammatory cytokines and chemokines, growth modulators, angiogenic factors and matrix metalloproteinases (for example, Mmp3 ) 37

SIRT3 suppression resulting from the enhanced -catenin signaling drives glycolysis and promotes hypoxia-induced cell growth in hepatocellular carcinoma cells

Nausea Vomiting Diarrhea Constipation Abdominal pain Indigestion Fatigue Though less common, serious side effects may include pancreatitis, gallbladder problems, kidney issues due to dehydration, and severe allergic or stomach reactions