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Liver metastasis from breast cancer reduced the metabolic reserve of the liver, and the systemic inflammatory response induced by chest wall and lung infection exacerbated the oxidative stress state, collectively constituting the vulnerable background for the patients susceptibility to drug toxicity

If any of these occur, consult your healthcare provider immediately

[20] In animals, since sulfur uptake is primarily obtained through the diet in the form of cysteine or methionine, the regulation of sulfur metabolism is done via the transsulfuration pathway

Eguchi R, Fujimori Y, Takeda H, Tabata C, Ohta T, Kuribayashi K, Fukuoka K, Nakano T (2011) Arsenic trioxide induces apoptosis through JNK and ERK in human mesothelioma cells