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Drugs induce ferroptosis by inhibiting the activity of the MAPK signaling pathway As an upstream signaling molecule of MAPK, the EGF receptor (EGFR) activates the RAS-ERK1/2 signaling pathway [132]

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[] In contrast to these good hepatokines for adipocytes, Fetuin-A (FetA) and dipeptidyl peptidase 4 (DPP4) are the examples of pro-inflammatory hepatokines for the adipose tissue