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van Bladeren et al

Menadione treatment depleted cellular GSH and reduced the GSH/glutathione disulfide ratio, but glutathione amino acid precursor supplementation effectively restored GSH levels and improved the redox balance

Curcumin increases Nrf2 expression and its downstream targets HO-1 and GPX4 in hepatocytes, 452 cardiomyocytes, 504 neurons, 679 renal tubule cells 865 and chondrocytes, 882 protecting against diseases by inhibiting ferroptosis