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[26] A complication of severe chronic PA is subacute combined degeneration of spinal cord, which leads to distal sensory loss (posterior column), absent ankle reflex, increased knee reflex response, and extensor plantar reflex response

& Gillies, P

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One study identified likely pathogenic variants within the RYR1 and CACNA1S genes for 16% of the investigated patients with statin-induced myopathy 19