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Methamphetamine modulates glutamatergic synaptic transmission in rat primary cultured hippocampal neurons

The increased inositol-requiring enzyme 1 expression by PFOS, which indicated endoplasmic reticulum (ER) stress activation, was associated with PFOS-mediated autophagy activation that could be attenuated through 4-phenylbutyrate (5 mM, an ER stress inhibitor) and l-Carnitine pretreatment

Similarly there was no significant correlation with ratings of anxiety or depression or length of illness

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