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Low Retinal Dehydrogenase 1 (RALDH1) Level in Prepubertal Boys with Autism Spectrum Disorder: A Possible Link to Dopamine Dysfunction

Oxidative stress and antioxidant deficits are observed when the hypothalamic-pituitary-adrenal (HPA) axis is excessively activated (Salim, 2017), among other brain structures, reduce neurogenesis (van Velzen et al., 2017), and contribute to cognitive dysfunction (Slavich et al., 2020)

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Active immunotherapy has also been explored, as demonstrated by PD01A, which showed favorable tolerability in early PD patients over six immunizations administered across five years