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But the second step in Class II involves a nucleophilic attack by the 3'-OH of the A76 ribose on the carboxyl carbon of the aminoacyl adenylate intermediate, forming aminoacyl-tRNA and AMP

As such, we were interested in checking whether NKG2D plays a role in mucosal Candida infections

The menstrual cycle has also been linked to oxidative stress 54,55

Beyond these mechanisms, TXNIP demonstrates mitochondrial translocation in hyperuricemic inflammation, where its interaction with NLRP3 induces inflammasome assembly and subsequent pro-inflammatory cytokine secretion (53)