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CrossRef Htd2 deficiency-associated suppression of -lipoic acid production provokes mitochondrial dysfunction and insulin resistance in adipocytes Mengqi Zeng, Jie Xu, Zhengyi Zhang, Xuan Zou, Xueqiang Wang, Ke Cao, Weiqiang Lv, Yuting Cui, Jiangang Long, Zhihui Feng, Jiankang Liu Redox Biology.2021

In addition, AMPK directly phosphorylates raptor and suppresses mTORC1 signaling [31] (Fig

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Following an initiating event, such as a reactive oxygen species, a hydrogen molecule is extracted from a CH bond that has been weakened by its proximity to an electron-withdrawing double bond found in polyunsaturated fatty acids, resulting in the formation of a carbon-centered radical (Niki, 2014, Valgimigli, 2023)