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Reverses 70% of 54 metastasis genes in colon cancer via Connectivity Map analysis.[9] Dose-Response: Biphasic Collagen synthesis stimulation begins at 10 M, peaks at 10 M (1 nanomolar) , and disappears at higher concentrations

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2 Otoprotection in Zebrafish Lateral Line Hair Cells Uribe et al., Frontiers in Cellular Neuroscience (2015) This paper from the Coffin laboratory (with WSU co-authors) tested whether Dihexa could protect zebrafish lateral line hair cells (homologous to mammalian inner ear hair cells) from aminoglycoside-induced ototoxicity