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10.3892/mmr.2021.12545 [DOI] [PMC free article] [PubMed] [Google Scholar] 124.Muchova L et al

Studies have indicated that editing the ApoE4 allele to the ApoE3 allele via gene-editing technologies leads to a reduction in ApoE fragmentation, A production, tau phosphorylation, and GABAergic neuron degeneration in iPSC-derived neurons, suggesting that the detrimental effects of ApoE4 could be alleviated through gene editing (Yamazaki et al., 2019

A seminal study in 2017 delved into the therapeutic potential of ferroptosis inhibitors, including Fer-1, deferoxamine, and vitamin E analogs [164], in mitigating cell toxicity induced by cerebral hemorrhage

Culture independent analysis of ileal mucosa reveals a selective increase in invasive escherichia coli of novel phylogeny relative to depletion of clostridiales in crohns disease involving the ileum