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With limited treatment options and no cure other than lung transplantation, there is an urgent need to understand the biological mechanisms that drive this disease

References: [1]Current Patent Assignee: GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT - WO2015/180612, 2015, A1

Exposure to GBB results in the upregulation of a specific microbial gene cluster, gbu (GBB utilizing), which is responsible for the conversion of GBB to TMAand more abundant in people who eat red meat

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