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According to a clinical study, three dietary intervention methods, including caloric limitation, intermittent fasting, and a ketogenic diet, positively intervene in mitochondrial respiratory function and increase cellular oxygen consumption rates

This strengthens the evidence that the adaptation and specialization of dimorphic Ajellomycetaceae occurred independently and that non-pathogenic Onygenaceae may represent an intermediate state in showing gene content changes associated with pathogens, which allowed these fungi to use proteins as a main source of energy in nutrient-limited environments

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