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RGCs, being terminally differentiated, are not able to regenerate themselves, and there are fewer efficient drugs for treating vision loss due to oxidative stress and apoptosis in RGCs 111,112,113 , in order to overcome this Qin and his colleagues used tert-butyl peroxide to develop RGC models of oxidative stress

Metabolic profiling, as an "overall model", has high specificity and can distinguish patient populations from healthy populations with considerable accuracy

No hypoxia-dependent change occurred in GCL or GS protein expression on Western blots

doi: 10.1186/S12870-024-04720-6/FIGURES/7 215 ZafarS.KhanS.IbrarD.KhanM