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These nonseroconverters include people on B-cell-depleting therapy or people with inborn errors of immunity, as these individuals are typically more susceptible to prolonged infection and higher rates of progression to severe disease [36, 37]

While bringing your own booze can be a harm reduction practice, in the case of BORGs, there are much more effective and safe ways to practice harm reduction when choosing to drink

The research paper, Ultra-high-dose methylcobalamin in amyotrophic lateral sclerosis: a long-term phase II/III randomised controlled study , was published in the Journal of Neurology, Neurosurgery & Psychiatry