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Prior to oocyte release, granulosa cells become luteinised by upregulating LHR expression, responding to human chorionic gonadotropin (hCG), and producing progesterone thus forming the corpus luteum in the secretory phase of the menstrual cycle

Our study provides a proof of principle that unique longevity mechanisms that evolved in long-lived mammalian species can be exported to improve the lifespans of other mammals, says Vera Gorbunova, the Doris Johns Cherry Professor of biology and medicine at Rochester

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