Recent efforts using machine learning approaches, targeted sequencing panels for genes involved in RASopathies (diseases that are a consequence of Ras pathway dysregulation, such as NF1), and open access data resources are attempting to address these challenges
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The aspirin-induced disruption of both acetyl-CoA synthesis and transport in EG110 yeast cells, may also have occurred as a consequence of dysfunctional mitochondria, already rendered prone to oxidative stress by their lack of MnSOD
References Sorokin O, Hause F, Wedler A, Alakhras T, Bauchspiess T, Dietrich A, et al
