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Proline is catalyzed by proline dehydrogenase enzyme (PRODH) to generate glutamate, which enters the TCA cycle to generate ATP and provides energy support for the activation of DCs and antigen presentation

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9: 2524 Foltz LM, Dalal BI, Wadsworth LD, et al

The Wells score is determined by major risk factors (recent history of surgery or bed rest, immobilization, or presence of cancer), physical exam findings (edema, engorgement, enlargement, tenderness, and superficial vein dilation in the affected limb), and history (previous DVT and absence of another likely explanation for signs and symptoms)