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Maintenance of skeletal muscle to counteract sarcopenia in patients with advanced chronic kidney disease and especially those undergoing hemodialysis

10.1001/jama.2017.17077 JAMA 97 KapellerJ.HoughtonL

Community oral protocols range from a 25 mg split-tablet pattern to a 50 mg or 100 mg daily pattern

Second, using senolytics too early results in stem cell depletion, accelerating the ageing process, whereas their delayed use may affect their effectiveness