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Blood Donors at the American Red Cross Whole-blood donation removes about 470 mL (a pint) of blood, which is way more than a typical lab draw (5 to 50 mL across all tubes)

Resources National Institute of Neurological Disorders and Stroke National Institute of Neurological Disorders and Stroke (additional information) Medline Plus Mayo Clinic

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Despite the possibility that additional mechanisms are also at play, the regulation of catalase expression seems to be primarily controlled at the transcriptional level