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Lescot M, Dhais P, Thijs G, Marchal K, Moreau Y, Van de Peer Y, et al

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They showed increased OS status in the testes and epididymides of hypertensive rats as evidenced by a significant reduction in total and non-protein thiol levels, glutathione S-transferase (GST) activity with a concomitant increase in DFCH oxidation and TBARS production

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Further, the rate and type of AEs experienced by the volunteers were indistinguishable from those experienced by the group receiving the placebo

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