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To view or add a comment, sign in Read our latest Review Article on #MetabolicCellDeath including #ferroptosis #cuproptosis #disulfidptosis in #CancerTherapy, published with Springer Nature in Nature Portfolio Boyi Gan Albert Koong Chao Mao Here we highlight the mechanisms of emerging metabolic cell death due to metabolic imbalances imposed by cancer cells, including excessive lipid peroxidation due to weakened cellular defense (ferroptosis), copper ion overload (cuproptosis) and disulfide stress (disulfidptosis)

Notably, area-specific LPS-induced inflammation in the intestine has been identified, and a unique gene signature may be useful to determine the affected intestinal region ( Supplementary Table 1 ) in the large intestine (109, 197)