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Additionally, zinc can block NMDA receptors, preventing glutamate from entering cells, thus producing an anxiolytic effect (Dou et al., 2018)

10.1016/j.neuron.2024.10.013 Neuron 134 OhS

Most studies note diminished prefrontal cortical activity in dorsolateral PFC, ventrolateral PFC, and dorsomedial PFC in depressed bipolar patients compared with either euthymic patients or healthy controls (90, 106, 141, 142)

These fragile neovessels are prone to rupture, leading to vision-threatening complications such as vitreous hemorrhage and tractional retinal detachment