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For instance, boiling fresh green beans and spinach caused no significant and 47% folate losses, resp., while that of frozen vegetables led to losses of 15% and 59%, resp., predominantly due to easier diffusion into the boiling water 379

There are specific scenarios where combining these two forms of B12 might be considered, as part of a tailored treatment plan: Reducing Injection Frequency: For some individuals who require lifelong B12 due to malabsorption but dislike frequent injections, a doctor might explore if high-dose oral supplements can help maintain adequate levels between less frequent injections