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through the non-oxidative phase, the synthesis of nucleotides will be supported by the provision of ribose-5-phosphate (to which external ribose can also contribute, if ribokinase is present)

Estrogen mutagenicity has also been demonstrated in transfected Big Blue rat2 embyronic cells 26 and Big Blue rats treated with 4-OHE 2 18

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The first and perhaps most straightforward of these mechanisms is increased mass-specific body oxygen stores which delay the onset of hypoxemia and tissue hypoxia and prolong submergence times (Ponganis et al., 1993