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Hyperpigmentation was observed when this compound got oxidized and inactivated by factors such as heat, radiation and inflammation with consequent loss of the inhibitory effect on tyrosinase

Critical Reviews in Food Science and Nutrition, 114

This phenomenon crosses over into radiotherapy resistance, where TGF- is thought to play a role in modulating treatment sensitivity and immune cell infiltration

2 Reported cases of APAP-induced hepatotoxicity first emerged in the United States in the mid-1980s, and since then all signs point towards a growing incidence